If you are a interested in learning more, download this brochures:


  Physician Brochure

  Scientific Article

  Patient Report

  Patient Brochure



3x Better than PSA
For Prostate Cancer Detection



Prostate Biopsy is Not Always Necessary


Order Now
(800) 766-8378

Leave a Message


SEND

PROSTATE HEATH INDEX (phi)

The Prostate Health Index (phi) is a calculation that uses a combination of three blood tests to produce a "phi score." This score provides more information about what elevated PSA levels might mean and the probability of finding prostate cancer on biopsy.*


The benefits of phi

phi is

  • A simple blood test for prostate cancer screening with FDA approval
  • A tool to reduce negative biopsies and provide more confidence in your biopsy decisions
  • A recommendation by the National Comprehensive Cancer Network (NCCN) Guidelines for PCa Early Detection

The Prostate Health Index (phi) is a calculation that uses a combination of three blood tests to produce a "phi" score: total PSA, free PSA and p2PSA. This score gives more accurate information on what an elevated PSA level might mean and the probability of finding cancer on biopsy.*

More confidence before a biopsy

Results from a prospective, multicenter clinical trial found that phi can provide better risk stratification versus % of PSA to identify patients that actually need a biopsy. More than 80 published clinical papers and meeting abstracts demonstrate the health benefits and economic value of phi.

Check out the clinical brochure >>


The power of phi

phi comprises a combination of three tests:
  • PSA
  • free PSA
  • p2PSA

The new p2PSA assay is specific to measuring [-2]proPSA. The [-2]proPSA biomarker is an isoform of free PSA that was identified as the most prostate cancer-specific form found in tumor extracts (1). The PSA, free PSA and p2PSA results are combined in the Beckman Coulter Access instrument to calculate a probability of prostate cancer.

Better Detection to Reduce Negative Biopsies

PSA is a widely used prostate cancer screening tool. However, with PSA’s limited specificity, a more precise tool is needed for prostate cancer detection. That tool was found in the discovery of phi. The phi score provides better risk stratification to identify patients who need a biopsy


How is phi used in clinical practice?

phi infographic


Because phi is three times more specific than PSA for detecting prostate cancer1, it fills the diagnostic gap between PSA testing and a prostate biopsy.

Combined with family and patient history, the phi results can be used to determine the best individualized patient management decisions.


Frequently asked questions (FAQs)

Q: Is phi (p2PSA) FDA-approved?
A: Yes, phi (p2PSA) received FDA approval in June 2012.

Q: Is phi in the National Comprehensive Cancer Network (NCCN)  Guidelines?
A: Yes, phi was first added to the NCCN Guidelines in 2014.

Q: Are there any clinical studies on phi available?
A: Yes. There are more than 80 published studies on phi from around the world. Your Beckman Coulter representative can provide a summary of these clinical studies.

Q: Do you have to run Beckman Coulter's PSA and fPSA assays to calculate phi?
A: Yes. phi is calculated using the test results from Beckman Coulter's PSA, fPSA and p2PSA, all using the same method of calibration.

Q: Is phi reimbursed?
A: CPT coding for reporting the calculation of phi is similar to coding for reporting the calculation of %free PSA. For %free PSA, labs have billed for both the PSA and free PSA tests when reporting %free PSA results. For phi, three national organizations, (American Urology Association / PRS Urology, CodeMap of Wheaton Partners, LLC) have all recommended that when reporting phi results, labs should bill for the PSA (CPT 84153), freePSA (CPT 84154), and p2PSA (CPT 86316) tests. All three CPT codes within the recommendations are listed on the Medicare Clinical Lab Fee Schedule (MCLFS).

Q: Is phi positioned as a first line repeat/confirm PSA or as a reflex after PSA is confirmed and in the 4 to 10 ng/mL range?
A: The phi labeling indicates it should be run after confirmation that PSA is in the 4-10 ng/mL range.*** This indication extends to both initial and repeat biopsies.  


*The phi results are intended to be used as an aid in distinguishing prostate cancer from benign prostatic conditions in men 50 years of age and older with total PSA results in the 4 – 10 ng/mL range and negative digital rectal examination (DRE) findings.

References:

  1. .Loeb S, Sanda MG, Broyles DL, et al. The prostate health index selectively identifies clinically significant prostate cancer. J Urol. 2015;193(4):1163-9.
  2. Beckman Coulter Access Hybritech p2PSA Instructions for Use


How to get phi

Register your contact details and set up an account with us.


New Account Request (800) 766-8378

* Start Date
Calendar
* Doctor First/Last Name
  Practice Name
* Email

Confirmation email will be sent to this address
* Office Street Address
* City
* State
* Zip Code
  Sales Rep. Name
* NPI #
* Office Phone
* Office Fax
  Automatic Pick Up:
  
  Hours
Mon Thu
Tue Fri
Wed Sat
  Result Delivery
  Hard Copy
  Web Access
  Automatic Fax
  EMR
  Software Name
  Contact Person
  Phone #
  Computer
  Special instructions
By clicking here and initialing below you verify that, to the best of your knowledge, none of the information entered into this form has been falsified or misrepresented.
 



SaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSaveSave

Find Lab Locations in Your State

Bayonne Patient Service Center #1
546 Ave C, Bayonne NJ 07002
Phone: (201) 471-7031
Hours: 7:30 AM - 5:00 PM
East Orange Patient Service Center
108 South Munn Ave, East Orange, NJ 07018
Phone: (862) 520-5315
Hours: 10:00 AM-5:00 PM
Florham Park Patient Service Center
15 James St, Florham Park, NJ 07932
Phone: (973) 301-1909
Hours: 9:00 AM - 5:00 PM
Glassboro Patient Service Center
359 N Main Street, Glassboro, NJ, 08028
Phone: (856) 881-5320
Hours: 7:30 AM-3:30 PM
Hoboken Patient Service Center
450 7th Street, Hoboken, NJ 07030
Phone: (201) 850-1437
Hours: 8:00 AM - 4:00 PM
Irvington Patient Service Center
40 Union Avenue, Suite 205, Irvington, NJ 07111
Phone: (862) 231-6223
Hours: 9:00 AM - 7:00 PM
Jersey City Patient Service Center
709 Newark Ave 2nd Floor, Jersey City, NJ 07036
Phone: (201) 222-0178
Hours: 9:00 AM - 5:00 PM
Somerset Patient Service Center
1553 Rt.27, Somerset, NJ, 08873
Phone: (908)583-6645
Hours: 10:00 AM - 2:00 PM
Succasunna Patient Service Center
262 Route 10 West, Succasunna, NJ 07876
Phone: (973) 970-9314
Hours: 9:00 AM - 4:00 PM
Toms River Patient Service Center
508 Lakehurst Rd, Suite 3B, Toms River, NJ 08755
Phone: (732) 228-7528
Hours: 7:30 AM - 4:00 PM
Woodbridge Patient Service Center
1030 St.Georges Avenue, Lower Level, Suite V, Avenel, NJ, 07001
Phone: (732) 326-2966
Hours: 9:00 AM - 5:00 PM
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
New Hyde Park Patient Service Center
1575 Hillside Avenue, Suite 100-A, New Hyde Park, New York, 11040
Phone: (516) 233-2585
Hours: 8:00 AM - 4:00 PM
Wappingers Falls Patient Service Center
66 Middlebush Rd. , Suite U300, Wappingers Falls, NY 12590
Phone: (845) 632-6262
Hours: 7:30 AM- 4:00 PM
Yonkers Patient Service Center
970 N Broadway, Suite 301, Yonkers, NY
Phone: (914) 207-1295
Hours: 7:00 AM - 4:00 PM
Have questions or need assistance? Call (877) 733-4522
Bridgeport Patient Service Center
754 Clinton Avenue, Bridgeport, CT, 06108
Phone: (203) 290-4775
Hours: 8:00 AM - 4:00 PM
Stamford Patient Service Center
Stamford Patient Service Center. 111 High Ridge Road, First Floor, Stamford, CT, 06905
Phone: (908) 583-6607
Hours: 8:00 AM - 4:00 PM
Waterbury Patient Service Center
Waterbury Patient Service Center. 2247 E.Main Street, Suite 103, Waterbury, CT 06705
Phone: (203) 574-2030
Hours: 8:00 AM - 5:00 PM
Have questions or need assistance? Call (877) 733-4522
Athol Patient Service Center
1467 Main Street, Athol, MA 01331
Phone: (978) 249-3825
Hours: 8:30 AM - 4:00 PM
Greenfield Patient Service Center
33 Riddell St, Greenfield, MA 01301
Phone: (413) 775-0000
Hours: 8:00 AM - 3:00 PM
Lancaster Patient Service Center
136 High Street Ext, Lancaster, MA 01523
Phone: (978) 368-6352
Hours: 8:00 AM - 5:00 PM
South Weymouth Patient Service Center
70 Pleasant Street, So Weymouth, MA, 02190
Phone: (908) 583-6610
Hours: 7:00 AM - 4:00 PM
Have questions or need assistance? Call (877) 733-4522
Cambridge Patient Service Center
10 Aurora Street, Cambridge, MD, 21613
Phone: (410) 228-0556
Hours: 8:00 AM - 5:00 PM
Have questions or need assistance? Call (877) 733-4522
Fayetteville Area Patient Service Center
905 Skibo Road, Suite 101, Fayetteville, NC, 28314
Phone: (910) 867-7071
Hours: 9:00 AM - 6:00 PM
Walter Reed Patient Service Center
1220 Walter Reed Road, Suite A, Fayetteville, NC, 28304
Phone: (910) 491-1956
Hours: 7:00 AM - 4:00 PM
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Bangor Patient Service Center
225 Erdman Avenue, Bangor, PA, 18013
Phone: (610) 452-9174
Hours: 7:00 AM- 3:00 PM
Hazelton Patient Service Center
101 South Church Street, Hazelton, PA 18704
Phone: (570) 455-0747
Hours: 8:00 AM - 4:00 PM
King Of Prussia Patient Service Center
491 Allendale Road, Ste 106, Kings Of Prussia, PA, 19406
Phone: (484) 679-1278
Hours: 9:00 AM - 5:00 PM
Kingston Patient Service Center
517 Pierce Street, Kingston, PA 18704
Phone: (570) 283-0674
Hours: 7:00 AM - 3:00 PM
Nanticoke Patient Service Center
233 South Prospect Street, Nanticoke, PA, 18634
Phone: (570) 735-2626
Hours: 7:00 AM - 1:00 PM
Have questions or need assistance? Call (877) 733-4522
Conlin Patient Service Center
4420 Conlin Street, Ste#100, Metairie, LA, 70006
Phone: (504) 302-2035
Hours: 8:00 AM - 5:00 PM
Lafayette Patient Service Center
850 Kaliste Saloom Road, Suite 111, Lafayette, LA, 70508
Phone: (337) 504-5926
Hours: 12:00 AM - 5:00 PM
Saxon Patient Service Center
4213 Saxon Street, Metairie, LA, 70006
Phone: (504) 779-8163
Hours: 7:00 AM - 4:00 PM
Have questions or need assistance? Call (877) 733-4522