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Respiratory Pathogen Panel (RPP)
Often, antibiotics are prescribed, however, using antibiotics can cause resistance among respiratory pathogens in individuals and in recent years an epidemic increase in antibiotic-resistant Streptococcus pneumoniae has been observed, prompting the need to decrease excess or inappropriate antibiotic use. ³
Multiplex Array simultaneously detects 21 viral and bacterial pathogens from the upper and lower respiratory tract. The array provides clinicians with a comprehensive infection profile for the patient enabling rapid and accurate diagnosis without the need for secondary or confirmatory testing to inform clinical treatment decisions. Identifying the infection correctly first time will reduce the misuse of antibiotics and improve their targeted use. Time to treatment is also reduced and unnecessary hospital stays are avoided.
Watch this video to see how Luminex’s next generation NxTAG® Respiratory Pathogen Panel, a highly multiplexed assay platform, allows the user to test a single sample to detect up to 21 different pathogens all in a single well.
Why Test for Respiratory Pathogens?
Many commonly encountered respiratory pathogens (viral and bacterial) have similar clinical presentation, making diagnosis based on symptoms alone very difficult. Influenza viruses commonly cause respiratory illness, but many other pathogens may cause significant impact on patient health as well. Respiratory syncytial virus (RSV), as one example, is the most common cause of severe respiratory illness in young children, as well as a leading cause of death from respiratory illness in those aged 65 years and older.
A clinician needs to accurately detect the respiratory pathogen causing illness in the patient in order to effectively prescribe treatment and control the spread of infection. Laboratories need respiratory assays that can rapidly and efficiently detect these relevant pathogens with minimal hands-on time and no post-PCR handling to meet laboratory, physician, and patient needs.
- Simultaneously detects 21 bacterial and viral pathogens from the upper and lower respiratory tract
- Enables identification of secondary or multiple infections
- Rapid turnaround time of six hours
- Reduced sample requirements and multiple sample types for patient comfort
- May prevent the spread of infection and reduce antibiotic misuse
- National Institute for Health and Care Excellence. Respiratory tract infections – antibiotic prescribing. Prescribing of antibiotics for self-limiting respiratory tract infections in adults and children in primary care. July 2008. Online. Available at: www.nice.org.uk. Last accessed 25 July 2014.
- Pavia, A.T. Viral Infections of the Lower Respiratory Tract: Old Viruses, New Viruses, and the Role of Diagnosis. Clinical Infectious Diseases. 2011:52 (Suppl 4) S284-289.
- Gonzales R, Bartlett JG, Besser RE, Cooper RJ, Hickner JM, Hoffman JR, et al. Principles of Appropriate Antibiotic Use for Treatment of Acute Respiratory Tract Infections in Adults: Background, Specific Aims, and Methods. Ann Intern Med. 2001;134:479-486.
- Seasonal Influenza & Other Respiratory Viruses. Centers for Disease Control (Internet). Cited 2015 March. Available from: http://www.cdc.gov/flu/about/qa/other.htm.
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