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Prealbumin is a transport protein. It plays a significant role in the metabolism of vitamin A by complexing with retinol-binding protein which in turn complexes with Vitamin A transporting it through the body. This protein is an acute phase reactant whose levels fall in inflammation, malignancy, cirrhosis of the liver and protein wasting diseases of the gut or kidneys. Decreases are associated with liver disease and malnutrition. Levels of Prealbumin increase in Hodgkins disease.
Immune complexes formed in solution scatter light in proportion to their size, shape and concentration. Turbidimeters measure the reduction of incident light due to reflection, absorption, or scatter.
Collect: Serum Separator Tube (SST) - 0.5 ml.
Specimen preparation: Serum free from hemolysis is the recommended specimens. Allow blood samples to clot (15 mins). Separate the serum from the cells by centrifuging for 10 minutes. Store serum at 2-8°C until analysis.
Stability: Serum samples are stable 7 days when stored 2 - 8°C. These samples can be stored frozen (≤ -20°C) for up to 2 months.
At Accu Reference: Refrigerated -7 days: Frozen- 1 monthNOTE: * This test is approved for all states. *
Accu Reference Medical Laboratory
Adults: 17 34 mg/dL
The Prealbumin turbidimetric procedure is linear from 3 - 80 mg/dL. Samples exceeding the upper limit of linearity are diluted and repeated.