Laboratory Test Directory


Code

Name



Overview of Clinical Trials

2017-10-10 06:00:00


What is clinical research?

 

Clinical trials are conducted to collect data regarding the safety and efficacy of new drug and device development. There are several steps and stages of approval in the clinical trials process before a drug or device can be sold in the consumer market, if ever.

Drug and device testing begins with extensive laboratory research which can involve years of experiments in animals and human cells. If the initial laboratory research is successful, researches send the data to the Food and Drug Administration (FDA) for approval to continue research and testing in humans.

Once approved, human testing of experimental drugs and devices can begin and is typically conducted in four phases. Each phase is considered a separate trial and, after completion of a phase, investigators are required to submit their data for approval from the FDA before continuing to the next phase.

 

Human Clinical Trial Phases

 

Phase I studies assess the safety of a drug or device. This initial phase of testing, which can take several months to complete, usually includes a small number of healthy volunteers (20 to 100), who are generally paid for participating in the study. The study is designed to determine the effects of the drug or device on humans including how it is absorbed, metabolized, and excreted. This phase also investigates the side effects that occur as dosage levels are increased. About 70% of experimental drugs pass this phase of testing.

Phase II studies test the efficacy of a drug or device. This second phase of testing can last from several months to two years, and involves up to several hundred patients. Most phase II studies are randomized trials where one group of patients receives the experimental drug, while a second "control" group receives a standard treatment or placebo. Often these studies are "blinded" which means that neither the patients nor the researchers know who has received the experimental drug. This allows investigators to provide the pharmaceutical company and the FDA with comparative information about the relative safety and effectiveness of the new drug. About one-third of experimental drugs successfully complete both Phase I and Phase II studies.

Phase III studies involve randomized and blind testing in several hundred to several thousand patients. This large-scale testing, which can last several years, provides the pharmaceutical company and the FDA with a more thorough understanding of the effectiveness of the drug or device, the benefits and the range of possible adverse reactions. 70% to 90% of drugs that enter Phase III studies successfully complete this phase of testing. Once Phase III is complete, a pharmaceutical company can request FDA approval for marketing the drug.

Phase IV studies, often called Post Marketing Surveillance Trials, are conducted after a drug or device has been approved for consumer sale. Pharmaceutical companies have several objectives at this stage: (1) to compare a drug with other drugs already in the market; (2) to monitor a drug's long-term effectiveness and impact on a patient's quality of life; and (3) to determine the cost-effectiveness of a drug therapy relative to other traditional and new therapies. Phase IV studies can result in a drug or device being taken off the market or restrictions of use could be placed on the product depending on the findings in the study.


 Source https://www.centerwatch.com/clinical-trials/overview.aspx



Make a Payment

To make our medical lab services easier to use we now offer a secure online payment service.

Home Visit Requisition Form

To request a home care services or to obtain more information on Accu reference medical lab, please complete an Home Visit Requisition Form

Career Opportunities

We are always interested in expanding our professional team. If you'd like to be considered for a position, send us your resume

E-Forms

This section contains e-forms. The forms may be printed and mailed or faxed.


Find a Location

East Orange Patient Service Center
108 South Munn Ave, East Orange, NJ 07018
Phone: (862) 233-6611
Hours:

10:00 AM-5:00 PM


Glassboro Patient Service Center
359 N Main Street, Glassboro, NJ 08028
Phone: (856) 881-5320
Hours:

7:30 AM-3:30 PM


Irvington Patient Service Center
40 Union Avenue, Suite 205, Irvington, NJ 07111
Phone: (862) 231-6223
Hours:

9:00 AM - 6:00 PM
CLOSED THURSDAYS AND WEEKENDS


Jersey City Patient Service Center
709 Newark Ave 2nd Floor, Jersey City, NJ 07036
Phone: (201) 222-0178
Hours:

9:00 AM - 5:00 PM


Linden Patient Service Center
1901 East Linden Avenue, Unit 25, Linden, NJ 07036
Phone: (908) 474-1004
Hours:

8:00 AM - 2:00 PM
CLOSED WEEKENDS


Somerset Patient Service Center
1553 Rt.27, Somerset, NJ 08873
Phone: (609) 528-9199
Hours:

9:00 AM - 6:00 PM
CLOSED WEEKENDS



Stamford Patient Service Center
111 High Ridge Road, First Floor, Stamford, CT 06905
Phone: (908) 583-6607
Fax: (908)224-9700
Hours:

9:00 AM - 3:00 PM

CLOSED WEDNESDAY, WEEKENDS



Baltimore Patient Service Center
3455 Wilkins Avenue, Suite L10-A, Baltimore, MD 21229
Phone: (410) 644-0075
Hours:

9:00 AM-3:39 PM


Brooklyn Patient Service Center
5908 5th Avenue, Suite 6, Brooklyn, NY 11220
Phone: (718) 439-8200
Hours:

9:00 AM-5:00 PM


Chappaqua Service Center
175 King Street, Chappaqua, NY 10514
Phone: (914)861-2439
Fax: (914)861-2440
Hours:

Monday, Wednesday 8:00 AM - 12:00 PM

Thursday, Friday       8:00 AM - 4:00 PM

CLOSED TUESDAY, WEEKENDS

 


New Hyde Park Patient Service Center
1575 Hillside Avenue, New Hyde Park, NY 11040
Phone: (516) 500-1047
Hours:

7:30 AM-4:00 PM



Medical Drive Patient Service Center
1314 Medical drive, Suite 101, Fayetteville, NC 28304
Phone: N/A
Hours:

8:30 AM-4:30 PM


Payetteville Patient Service Center I
1905 Skibo Road, Suite 101, Fayetteville, NC 28314
Phone: (910) 867-7071
Hours:

9:00 AM-6:00 PM


Walter Reed Patient Service Center
1220 Walter Reed Road, Suite A, Fayetteville, NC 28304
Phone: (910) 491-1956
Hours:

7:00 AM - 4:00 PM



Bangor Patient Service Center
225 Erdman Avenue, Bangor, PA 18013
Phone: (610) 452-9174
Hours:

7:00 AM- 3:00 PM


Hazelton Patient Service Center
101 South Church Street, Hazelton, PA 18704
Phone: (570) 455-0747
Hours:

8:00 AM - 4:00 PM


Kingston Patient Service Center
517 Pierce Street, Kingston, PA 18704
Phone: (570) 283-0674
Hours:

7:00 AM - 3:00 PM


Nanticoke Patient Service Center
233 South Prospect Street, Nanticoke, PA 18634
Phone: (570) 735-2626
Hours:

7:00 AM - 1:00 PM



Conlin Patient Service Center
4420 Conlin Street, Ste#100, Metairie, LA 70006
Phone: (504) 302-2035
Hours:

8:00 AM - 5:00 PM


Saxon Patient Service Center
4213 Saxon Street, Metairie, LA 70006
Phone: (504) 779-8163
Hours:

7:00 AM - 4:00 PM


West Bank Patient Service Center
1799 Stumpf blvd, Gretna, LA 70056
Phone: (504) 301-1817
Hours:

N/A



Have questions or need assistance? Call (877) 733-4522