Laboratory Test Directory

Celiac Disease Screening

Posted on: 11.06.2019

Normally, your immune system attacks things like viruses and bacteria. If you have celiac disease, eating gluten makes your immune system attack the lining of the small intestine, as if it were a harmful substance. This can damage your digestive system and may prevent you from getting the nutrients you need.

Other names: celiac disease antibody test, anti-tissue transglutaminase antibody (anti-tTG), deaminated gliadin peptide antibodies, anti-endomysial antibodies

What is it used for?

A celiac disease test is used to:

  • Diagnose celiac disease
  • Monitor celiac disease
  • See if a gluten-free diet is relieving symptoms of celiac disease

Why do I need a celiac disease test?

You may need a celiac disease test if you have symptoms of celiac disease. Symptoms are different for children and adults.

Symptoms of celiac disease in children include:

  • Nausea and vomiting
  • Abdominal bloating
  • Constipation
  • Chronic diarrhea and foul-smelling stool
  • Weight loss and/or failure to gain weight
  • Delayed puberty
  • Irritable behavior

Symptoms of celiac disease in adults include digestive problems such as:

  • Nausea and vomiting
  • Chronic diarrhea
  • Unexplained weight loss
  • Decreased appetite
  • Abdominal pain
  • Bloating and gas

Many adults with celiac disease have symptoms that are not related to digestion. These include:

  • Iron-deficient anemia
  • An itchy rash called dermatitis herpetiformis
  • Mouth sores
  • Bone loss
  • Depression or anxiety
  • Fatigue
  • Headaches
  • Missed menstrual periods
  • Tingling in the hands and/or feet

If you don't have symptoms, you may need a celiac test if you are at higher risk of having the disease. You are more likely to have celiac disease if a close family member has celiac disease. You may also be at higher risk if you have another autoimmune disorder, such as type 1 diabetes.

What happens during a celiac disease test?

A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Will I need to do anything to prepare for the test?

If the test is being used to diagnose celiac disease, you'll need to continue to eat foods with gluten for a few weeks before testing. Your health care provider will give you specific instructions about how to prepare for the test.

If the test is being used to monitor celiac disease, you don't need any special preparations.

Are there any risks to the test?

There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.

What do the results mean?

There are different types of celiac disease antibodies. Your celiac test results may include information on more than one type of antibody. Typical results may show one of the following:

  • Negative: You probably don't have celiac disease.
  • Positive: You probably do have celiac disease.
  • Uncertain or indeterminate: It's unclear whether you have celiac disease.

If your results were positive or uncertain, your provider may order a test called an intestinal biopsy to confirm or rule out celiac disease. During an intestinal biopsy, a health care provider will use a special tool called an endoscope to take a small piece of tissue from your small intestine.

Is there anything else I need to know about a celiac disease test?

Most people with celiac disease can reduce and often eliminate symptoms if they keep a strict gluten-free diet. Although many gluten-free products are available today, it can still be challenging to completely avoid gluten. Your health care provider may refer you to a dietician who can help you enjoy a healthy diet without gluten.

References

  1. MedlinePlus [Internet]. Available from: https://medlineplus.gov/lab-tests/celiac-disease-screening/
  2. American Gastroenterological Association [Internet]. Bethesda (MD): American Gastroenterological Association; c2018. Understanding Celiac Disease [cited 2018 Apr 27]; [about 3 screens]. Available from: http://www.gastro.org/patient-center/brochure_Celiac.pdf
  3. Celiac Disease Foundation [Internet]. Woodland Hills (CA): Celiac Disease Foundation; c1998–2018. Celiac Disease Screening and Diagnosis [cited 2018 Apr 27]; [about 3 screens]. Available from: https://celiac.org/celiac-disease/understanding-celiac-disease-2/diagnosing-celiac-disease
  4. Celiac Disease Foundation [Internet]. Woodland Hills (CA): Celiac Disease Foundation; c1998–2018. Celiac Disease Symptoms [cited 2018 Apr 27]; [about 3 screens]. Available from: https://celiac.org/celiac-disease/understanding-celiac-disease-2/celiacdiseasesymptoms
  5. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2018. Autoimmune Disorders [updated 2018 Apr 18; cited 2018 Apr 27]; [about 3 screens]. Available from: https://labtestsonline.org/conditions/autoimmune-diseases
  6. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2018. Celiac Disease Antibody Tests [updated 2018 Apr 26; cited 2018 Apr 27]; [about 2 screens]. Available from: https://labtestsonline.org/tests/celiac-disease-antibody-tests
  7. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2018. Celiac Disease: Diagnosis and Treatment; 2018 Mar 6 [cited 2018 Apr 27]; [about 4 screens]. Available from: https://www.mayoclinic.org/diseases-conditions/celiac-disease/diagnosis-treatment/drc-20352225
  8. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2018. Celiac Disease: Symptoms and Causes; 2018 Mar 6 [cited 2018 Apr 27]; [about 3 screens]. Available from: https://www.mayoclinic.org/diseases-conditions/celiac-disease/symptoms-causes/syc-20352220
  9. Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co. Inc.; c2018. Celiac Disease [cited 2018 Apr 27]; [about 2 screens]. Available from: https://www.merckmanuals.com/home/digestive-disorders/malabsorption/celiac-disease
  10. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests [cited 2018 Apr 27]; [about 3 screens]. Available from: https://www.nhlbi.nih.gov/health-topics/blood-tests
  11. National Institute of Diabetes and Digestive and Kidney Diseases [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Definitions and Facts for Celiac Disease; 2016 Jun [cited 2018 Apr 27]; [about 4 screens]. Available from: https://www.niddk.nih.gov/health-information/digestive-diseases/celiac-disease/definition-facts
  12. National Institute of Diabetes and Digestive and Kidney Diseases [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Treatment for Celiac Disease; 2016 Jun [cited 2018 Apr 27]; [about 7 screens]. Available from: https://www.niddk.nih.gov/health-information/digestive-diseases/celiac-disease/treatment
  13. UF Health: University of Florida Health [Internet]. University of Florida; c2018. Celiac disease—sprue: Overview [updated 2018 Apr 27; cited 2018 Apr 27]; [about 2 screens]. Available from: https://ufhealth.org/celiac-disease-sprue
  14. University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2018. Health Encyclopedia: Anti-tissue Transglutaminase Antibody [cited 2018 Apr 27]; [about 2 screens]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=antitissue_transglutaminase_antibody
  15. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2018. Celiac Disease Antibodies: How To Prepare [updated 2017 Oct 9; cited 2018 Apr 27]; [about 4 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/celiac-disease-antibodies/abq4989.html#abq4992
  16. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2018. Celiac Disease Antibodies: Results [updated 2017 Oct 9; cited 2018 Apr 27]; [about 8 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/celiac-disease-antibodies/abq4989.html#abq4996
  17. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2018. Celiac Disease Antibodies: Test Overview [updated 2017 Oct 9; cited 2018 Apr 27]; [about 2 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/celiac-disease-antibodies/abq4989.html#abq4990
  18. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2018. Celiac Disease Antibodies: Why It is Done [updated 2017 Oct 9; cited 2018 Apr 27]; [about 3 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/celiac-disease-antibodies/abq4989.html#abq4991

Find Lab Locations in Your State

East Orange Patient Service Center
108 South Munn Ave, East Orange, NJ 07018
Phone: (862) 233-6611
Hours: 10:00 AM-5:00 PM
Glassboro Patient Service Center
359 N Main Street, Glassboro, NJ, 08028
Phone: (856) 881-5320
Hours:
Irvington Patient Service Center
40 Union Avenue, Suite 205, Irvington, NJ 07111
Phone: (862) 231-6223
Hours: 9:00 AM - 7:00 PM
Jersey City Patient Service Center
709 Newark Ave 2nd Floor, Jersey City, NJ 07036
Phone: (201) 222-0178
Hours: 9:00 AM - 5:00 PM
Linden Patient Service Center
1901 East Linden Avenue, Unit 25, Linden, NJ, 07036
Phone: (908) 474-1004
Hours: 8:00 AM - 2:00 PM
Somerset Patient Service Center
1553 Rt.27, Somerset, NJ, 08873
Phone: (908)583-6645
Hours: 9:00 AM - 6:00 PM
Have questions or need assistance? Call (877) 733-4522
Bridgeport Patient Service Center
754 Clinton Avenue, Bridgeport, CT, 06108
Phone: (203) 290-4775
Hours: 8:00 AM - 4:00 PM
Stamford Patient Service Center
111 High Ridge Road, First Floor, Stamford, CT, 06905
Phone: (908) 583-6607
Hours: 9:00 AM - 5:00 PM
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Tampa Patient Service Center
3610 Galileo Dr., Suite 103, New Port Richey, FL, 34655
Phone: (727) 845-4999
Hours: 8:00 AM - 3:30 PM
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Brooklyn Patient Service Center
5908 5th Avenue, Suite 6 , Brooklyn, NY, 11220
Phone: (718) 439-8200
Hours: 9:00 AM - 5:00 PM
New Hyde Park Patient Service Center
1575 Hillside Avenue, New Hyde Park, NY, 11040
Phone: (516) 500-1047
Hours: 7:30 AM - 4:00 PM
Have questions or need assistance? Call (877) 733-4522
Fayetteville Patient Service Center I
1905 Skibo Road, Suite 101, Fayetteville, NC, 28314
Phone: (910) 867-7071
Hours: 9:00 AM - 6:00 PM
Medical Drive Patient Service Center
1314 Medical drive, Suite 101, Fayetteville, NC
Phone:
Hours: 8:30 AM - 4:30 PM
Walter Reed Patient Service Center
1220 Walter Reed Road, Suite A, Fayetteville, NC, 28304
Phone: (910) 491-1956
Hours: 7:00 AM - 4:00 PM
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Bangor Patient Service Center
225 Erdman Avenue, Bangor, PA, 18013
Phone: (610) 452-9174
Hours: 7:00 AM- 3:00 PM
Hazelton Patient Service Center
101 South Church Street, Hazelton, PA 18704
Phone: (570) 455-0747
Hours: 8:00 AM - 4:00 PM
Kingston Patient Service Center
517 Pierce Street, Kingston, PA 18704
Phone: (570) 283-0674
Hours: 7:00 AM - 3:00 PM
Nanticoke Patient Service Center
233 South Prospect Street, Nanticoke, PA, 18634
Phone: (570) 735-2626
Hours: 7:00 AM - 1:00 PM
Have questions or need assistance? Call (877) 733-4522
Conlin Patient Service Center
4420 Conlin Street, Ste#100, Metairie, LA, 70006
Phone: (504) 302-2035
Hours: 8:00 AM - 5:00 PM
Saxon Patient Service Center
4213 Saxon Street, Metairie, LA, 70006
Phone: (504) 779-8163
Hours: 7:00 AM - 4:00 PM
West Bank Patient Service Center
1799 Stumpf blvd, Gretna, LA 70056
Phone: (504) 301-1817
Hours:
Have questions or need assistance? Call (877) 733-4522
Have questions or need assistance? Call (877) 733-4522
Physician & Hospital Lab Services, Nevada (NV): Partnership
Headquarters: 1901 East Linden Ave, Suite 12, Linden NJ
Phone: (800) 295-0529 Contact a Sales Rep
Hours:
Physician & Hospital Lab Services, Ohio (OH): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Oklahoma (OK): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Oregon (OR): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Alabama (AL): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Alaska (AK): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Arizona (AZ): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Arkansas (AR): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Colorado (CO): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Connecticut (CT): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Delaware (DA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Florida (FL): Partnership
2700 N 29th Ave, Suite 301, Hollywood, FL 33020
Phone: 954-237-7711
Hours:
Physician & Hospital Lab Services, Georgia (GA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Hawaii (HI): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Idaho (ID): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Illinois (IL): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Indiana (IN): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Iowa (IA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Kansas (KS): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours: 24H
Physician & Hospital Lab Services, Kentucky (KY): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Louisiana (LA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Maine (ME): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Maryland (MD): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Massachusetts (MA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Michigan (MI): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Minnesota (MN): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Missouri (MO): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Nebraska (NE): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, New Hampshire (NH): Partnership
Accu Reference Medical Lab, New Hampshire, NH
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, New Jersey (NJ): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours: 24H
Physician & Hospital Lab Services, New Mexico (NM): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, New York (NY): Partnership
Accu Reference Medical Lab, New York NY
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, North Carolina (NC): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, North Dakota (ND): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Pennsylvania (PA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Rhode Island (RI): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, South Carolina (SC): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, South Dakota (SD): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Tennessee (TN): Partrnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Texas (TX): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Utah (UT): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Vermont (VT): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Virginia (VA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Washington (WA): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, West Virginia (WV): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Wisconsin (WI): Partnership
Accu Reference Medical Lab, Wisconsin, WI
Phone: (800) 295-0529
Hours:
Physician & Hospital Lab Services, Wyoming (WY): Partnership
Accu Reference Medical Lab
Phone: (800) 295-0529
Hours:
Physician, Healthcare Provider & Hospital Lab Services, Montana (MT): Partnership
Headquarters: 1901 East Linden Ave, Suite 12, Linden NJ
Phone: (800) 295-0529 Contact a Sales Rep
Hours: 9:00 AM - 7:00 PM
Have questions or need assistance? Call (877) 733-4522